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J Neural Transm (Vienna) 124:15671605 Fanciulli A, Campese N, Wenning GK (2019) The Schellong test: detecting orthostatic blood pressure and heart rate changes in German-speaking countries

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For example, VEGFA induces ROS in endothelial cells in a NADPH oxidase/rac1dependent manner that lead to autophosphorylation of the VEGFA receptor Flk1 and downstream activation of AKT and ERK, resulting in increased endothelial cell migration and proliferation, and antioxidants inhibited the mitogenic effects of VEGFA in endothelial cells (Abid et al , 2000