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Cells were transfected with AAV shuttle vector (7 g per 15 cm dish), Rep/Cap plasmids (7 g per 15 cm dish) and F6 helper plasmids (20 g per 15 cm dish) using polyethyleneimine

Carbocisteine was found to be safe and well tolerated in all studies

Serrano LM, Molenaar D, Wels M, Teusink B, Bron P, de Vos W, Smid E: Thioredoxin reductase is a key factor in the oxidative stress response of Lactobacillus plantarum WCFS1