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The active ingredient in the liver remained unknown until 1948

If any of the following sound familiar, a B12 deficiency could be the root cause: You feel exhausted even after a full nights sleep Mental fog or trouble focusing during the day Heavy caffeine dependence to get through work Regular afternoon energy crashes A lack of motivation despite no changes in routine Instead of pushing through with stimulants, addressing the underlying deficiency could provide longer-lasting relief

This suggests that the process of GSH-mediated ROS detoxification has important influence on the level of [ROS] during retinal development and degeneration