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Despite the different pathways leading to cell death, there is a significant crosstalk between them, which depends on the cellular and tissue context, such as after PD lesion stimuli in animal models (Hartmann et al., 2001

2022 Jun 1 [cited

Spinosa M, Su G, Salmon MD, Lu G, Cullen JM, Fashandi AZ, et al

This study marked the first biochemical evidence suggesting that H 2 O 2 produced by colonic epithelial cells is the previously unidentified chemical secreted by colonic epithelial cells leading to the development of UC