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Injecting at too shallow an angle can result in intradermal injection (too shallow, medication stays in the skin) or the needle glancing off rather than penetrating cleanly

The dose chosen was based on an initial dose escalation study (ranging from 10 mg/kg/day to a total dose of 150 mg/kg/day) in DIO mice (n=2)

[194] Specific populations Pfizer and BioNTech started a Phase IIIII randomized control trial in healthy pregnant women 18 years of age and older (NCT04754594)