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Mizushima N, Levine B

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The therapeutic potential of GGV is further underscored by its role in modulating the liver-microbiota-gut axis, a complex system of interactions in which gut-derived metabolites influence liver function, while the liver, in turn, regulates the gut microbiota through bile acid release

The retro-inverso D-amino acid configuration of FOXO4-DRI confers resistance to proteolytic enzymes, a pharmacokinetic property critical for maintaining peptide stability in complex biological research environments