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Cognitive decline is a common feature of the aging nervous system and is a key risk factor for neurodegenerative diseases including Alzheimers disease (AD), which is characterized by progressive memory loss and a decline in mental capacity 1

Consequently, it is a highly credible candidate gene, particularly since serological tests conducted in the mid-1970s found a correlation between psoriasis and the HLA-Cw6 allele (Chen and Tsai 2018)

The use of bNAb-instructed stabilization of HIV Env trimers is the basis for many promising immunogens 311

There are many theorized causes of AD, one of the main causes being metabolic dysfunction (Cai et al., 2012)