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GPx2 knockout in murine models has been associated with intestinal tumorigenesis and increased susceptibility to skin cancer following irradiation (Brigelius-Floh And Kipp 2009)

However, this may not be as clinically meaningful as paraprotein trajectories as levels can fluctuate although this is the period of highest dietary adherence

PLoS ONE 9 , e106028 (2014)

Vitamin B12 Overdose This article was reviewed by Kelly Brown MD, MBA Vitamin B12 overdose is so rare that serious adverse effects from consuming large amounts of vitamin B12 have only been reported in a handful of studies in the medical literature