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doi: 10.1016/0016-5085(83)90312-8 153 JinJByunJKChoiYKParkKG

Proinflammatory cytokines such as Tumor Necrosis Factor (TNF)-, interleukin (IL)-1 or IL-18 induce the endocytosis of epithelial apical junctional proteins [120], promoting an increment in intestinal permeability [121]

[DOI] [PubMed] [Google Scholar] 14.Sikiric P., Seiwerth S., Rucman R., Turkovic B., Rokotov D.S., Brcic L., Sever M., Klicek R., Radic B., Drmic D., et al

The oxidized form has already donated its electrons, so it is not effective as an antioxidant because the sulfur group which allows it to bind to metals is already bound to another oxidized glutathione molecule and is not available for use for detoxification