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Author contributions ZH: Conceptualization, Methodology, Software, Validation, Visualization, Writing original draft, Writing review and editing

It can be useful for older men with GH insufficiency or metabolic contributors to poor semen quality

Moreover, we treated primary ESCs with cyst fluid in vitro and found a markedly elevated level of lipid ROS and shrunk mitochondria with increased membrane density, indicating that ESC ferroptosis was induced by the chocolate cyst fluid

On the contrary, healthy tissue displayed higher levels of extracellular oxidative stress, which could be a consequence of better vascularization and therefore oxygen availability in healthy lung tissue: while the reported oxygen concentration for healthy lung tissue is ~5.6%, for lung tumors this value drops to ~2%, and in some extreme cases even to as low as 0.1% 26,27