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Second, N-hydroxy-L-arginine is oxidized to L-citrulline and NO with the aid of L-arginine and co-factor BH 4 (Fig

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Ludtmann MHR, Angelova PR, Horrocks MH, Choi ML, Rodrigues M, Baev AY, Berezhnov AV, Yao Z, Little D, Banushi B, Al-Menhali AS, Ranasinghe RT, Whiten DR, Yapom R, Dolt KS, Devine MJ, Gissen P, Kunath T, Jaganjac M, Pavlov EV, Klenerman D, Abramov AY, Gandhi S (2018) alpha-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinsons disease