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De Smet et al., 2013)

The dorsogluteal site has been phased out of current guidance because of its proximity to the sciatic nerve and superior gluteal artery

Or, place it in the refrigerator for a few minutes

Thus, the available data largely support the notion that NAC could be used orally, increasing plasma levels of glutathione and acting as a replenisher of this endogenous scavenger (Kopke et al., 2007