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Second, this redox imbalance activates stress-sensitive signaling cascades (e.g

Computed tomography (CT) revealed multiple masses in the abdomen, liver, and kidneys, with mild sternal and splenic hilar lymphadenopathy

For broader clinical use, however, these benefits require systematic and well-designed clinical validation (64)

NRF2 provides a protective effect in melanocytes in response to both UV irradiation and oxidative stress 30,31 , through transcriptional upregulation of the antioxidant response element (ARE) genes including Superoxide dismutase-1 (SOD-1), Glutathione peroxidase-1 (GP-1), Glutathione reductase-1 (GR-1), Catalase and Heme oxygenase-1 (HO-1) 38,39,40