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DFO, while effective in animal models, exhibits poor bloodbrain barrier (BBB) permeability, necessitating intranasal or intracerebroventricular delivery to achieve therapeutic concentrations (Guo et al., 2013)

Apr 3 2023;69(4):336-349

10.1016/j.tips.2020.11.009 95 MaY.ThurechtK

This free radical-mediated damage is considered as the initial pathogenic event in degeneration of melanocyte in generalized vitiligo and supplementing glutathione, which is a potent antioxidant, in vitiligo patients may prove to have therapeutic effect