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Patients with darker skin tones may also be prone to hyperpigmentation, where the scar area becomes darker than the surrounding skin

Copper overload or overmethylation may cause panic, irritability, insomnia, appetite loss, hypertension or emotional overactivation

Due to their high metabolic rate, neurons are particularly susceptible to damage from ROS, and copper serves a crucial role in antioxidant defense (71)

5.16 Crystalluria Crystals of ciprofloxacin have been observed rarely in the urine of human subjects but more frequently in the urine of laboratory animals, which is usually alkaline [see Nonclinical Toxicology (13.2)]