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Despite multiple trials supporting its efficacy in reducing the risk of relapse and increasing abstinence days (Agabio et al., 2023), its efficacy remains controversial, and systematic reviews consider the evidence of its efficacy insufficient (Jonas et al., 2014)

Kara Andrew, RDN, LDN Medical Reviewer Kara Andrew, RDN, LDN, is the director of health promotion for Memorial Hospital in Carthage, Illinois

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Furthermore, NT-enhanced collagen promoted fibroblast accumulation in granulation tissue and stimulated collagen production and deposition at the wound site, ultimately leading to a more organized and mature collagen matrix [197]