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Mouse fibroblast cells NIH/3T3 (SCSP-515), mouse fibroblast cells L-929 (SCSP-5039) and mouse macrophage cells RAW 264.7 (SCSP-5036) were purchased from Chinese Academy of Science Cell Bank for Type Culture Collection (Shanghai, China)

The IRAP inhibitor 48 was the best inhibitor in a second series of bioisosteric diaminobenzoic acid inhibitors but was both less potent and selective as compared 47 (Papakyriakou et al., 2015)