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doi:10.1172/jci.insight.159762

The inconvenience of its dosing mechanism may make it a less popular option

10.1097/00007632-199909010-00003 280 TamV.ChenP.YeeA.SolisN.KleinT.KudelkoM.et al (2020)

Mechanically, the lactate produced by the CAFs can be used by cancer cells, thus enhancing aerobic glycolysis, which is called the reverse Warburg effect (28, 272)