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Data and code availability The code generated during this study is available at METHOD DETAILS Hepatocyte specific model Starting with the thermodynamically curated human genome-scale Recon 3D 31,32 , we reconstructed a hepatocyte metabolic model by taking into account the physiology of hepatocytes and the genes expressed in liver cells

After 30 min incubation at 37 C Waymouth media was added on top

Developing models to predict these combined effects under different conditions would provide a deeper understanding of the complex interactions

Moisturizing is an essential step in a skin care routine to reduce melanin pigmentation