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Consistent with the in vitro results above, transfer of Lip-1 ex vivotreated 2C CD8 + T cells significantly inhibited tumor growth in B16-SIYbearing mice (Supplemental Figure 2, AC) accompanied by an increased accumulation and effector function of transferred CD8 + T cells within tumors (Supplemental Figure 2, DH)

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Moreover, this indicated that both, the extension of the reaction time and the increase of the excess of reducing agent, do not affect the decrease of N-Hcy-Lys signal

sulfurreducens assays (Thomas et al., 2018), but the fate of exogenous cysteine at more typical environmental concentrations (nM) is unknown