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Some peptides or related compounds are FDA-approved for specific indications, while many peptide therapies are not FDA-approved for general clinical use and are offered as part of innovative or investigational medical programs outside the United States

Additionally, curcumin restores UV-induced mutant p53 function by modulating B-cell lymphoma 2 Associated X Protein/B-cell lymphoma 2(Bax/Bcl-2)balance, reversing apoptosis resistance and improving mitochondrial homeostasis (Rebel et al., 2012)

Managing Treatment-Resistant Depression in Road to Novel Therapeutics 2022 237-51

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