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Rimbara, E., Mori, S., Kim, H

Statements Acknowledgments Funding Source : This study was supported by an internal award from the Childrens Healthcare of Atlanta Friends grant number 38234, by RO1 NR012021, and by award number UL1TR000454 from the National Center for Advancing the Translational Sciences

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Redox potential, calculated using the Nernst equation, accounts for the stoichiometry of two electron transfers as two GSH are involved in the oxidation to GSSG ( h Cys/CySS and E h GSH/GSSG in serum is that it provides an overall measure of the pro-oxidant/anti-oxidant balance ( Fitzpatrick and colleagues have measured the E h Cys/CySS and E h GSH/GSSH of mild-to-moderate and severe asthmatics ( h Cys/CySS 65 mV) have a significantly more oxidized Cys/CySS redox potential than mild-to-moderate asthmatics (mean E h Cys/CySS 95 mV) and are similarly oxidized to severe asthmatics in the Fitzpatrick study (mean E h Cys/CySS 55 mV)