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Effects of theaflavins supplementation on growth performance and blood parameters in mice fed high-iron diets

These results suggest the high tumor growth inhibition effect of NP4 against aggressive osteosarcoma inside the animal model

Several non-oxidant apoptogenic agents such as tumor necrosis factor (Lee et al., 2002) and cycloheximide (Zhao et al., 2011) also elicit oxidative stress, indicating that ROS generation may be a conserved apoptotic event

473,474 AMPK activate peroxisome proliferator-activated receptor coactivator-1 (PGC-1), the key factor in mitochondrial biogenesis, thus enhancing mitochondrial respiratory and metabolic functions