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Presented by Zhao et al, the protein expression of PTEN was upregulated, while the expression level of MMP-9 was decreased in Ishikawa cells treated with kaempferol

Furthermore, spine care is shifting towards more personalized treatments through biologic and regenerative approaches

Upon tissue injury, locally released SDF-1 forms a chemotactic gradient that binds to CXCR4 expressed on the MSC surface, initiating intracellular signaling that guides MSC migration to the injury site ( The paracrine effect of MSCs complements their homing capability, together forming a critical defense mechanism against high-altitude-induced tissue injury

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