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Subgroup analysis also demonstrated mean decreases from baseline in LDL-C at Week 24 of approximately 36% in patients receiving LDL apheresis at baseline and 62% in patients not receiving LDL apheresis at baseline

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After 12 weeks: 73% reported significant discomfort reduction 41% noted decreased testicular heaviness Scrotal skin examination showed 58% reduction in heat-related irritation Among patients with oligospermia, 29% showed improved sperm parameters at 6-month follow-up Best for: Grades II-III varicocele, active lifestyles, warm climates, patients with significant daytime discomfort