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461 It is thought that magnesiums poor ability to cross the blood-brain barrier may be responsible for its weak performance in clinical trials

Biochim Biophys Acta BBA-Mol Cell Biol Lipids 1863(9):10951107

Summary Keywords endocrinology, growth hormone secretagogues, IGF-1 analogues, off-label use, peptide hormones, performance-enhancing drugs, sports doping Citation Dominikowski A, Rko Z, Olejarz M, Szczepanek-Parulska E, Domin R and Ruchaa M (2026) The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration