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We divide DVT into two categories: provoked and unprovoked. Provoking risk factors include: not getting up to move around very much during extensive travel major surgery causing vascular injury, prolonged hospitalization and/or limited mobility trauma fractures, such as a broken leg or rib malignancies requiring active treatment medications, such as estrogen therapy high body weight pregnancy smoking inherited conditions such as factor V Leiden, antiphospholipid syndrome and autoimmune disorders