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doi:10.1523/JNEUROSCI.0542-14.2014 Agnello D, Villa P, Ghezzi P (2000) Increased tumor necrosis factor and interleukin-6 production in the central nervous system of interleukin-10-deficient mice

A medical evaluation may include history, medication review, physical examination, stool testing when appropriate, blood work, inflammatory markers, nutrient testing, thyroid review, metabolic markers, referral for gastroenterology evaluation, or other targeted steps depending on the symptoms

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However, people who eat healthy food and refrain from alcohol can still develop the condition