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Description

Of the 11 patients with blood cyanide exceeding the typically lethal threshold of 100 micromol/L, 7 survived

Neurosurgery 93 , 10751081 (2023)

5-Amino-1MQ targets the substrate binding site of NNMT the nicotinamide binding pocket competitively inhibiting nicotinamide methylation with an IC50 of 1.2 M under reference assay conditions