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In the mouse brain, the activity of the pathway is lower as compared to the liver, but the flux can be increased by oxidative stress (Vitvitsky et al., 2006

Reduced expression of the O-mannosyltransferase 2 (AfPmt2) leads to deficient cell wall and abnormal polarity in Aspergillus fumigatus

Glycolysis converts the 13 C-glucose tracer to M3-pyruvate isotopologues which are oxidized to M2-acetyl-CoA by PDC and finally condensed with oxaloacetate to M2-citrate