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This work was financially supported by the Strategic Priority Research Program (No

10.1016/j.lfs.2017.12.025 36 DarrJ.HamamaZ

Zhao et al., 2019) (Table 2)

While agonist peptides based on either scaffold are potent in rat obesity models 2,10,11,12,13 , only a transient weight loss effect is observed with sCT in mouse diet-induced obesity (DIO) models 14 , indicating that there may be distinctions in the mode of action of individual dual agonists