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Now, Johnson says he has been diagnosed with autoimmune gastritis (AIG), a chronic autoimmune disease in which the immune system attacks the stomach's acid-producing parietal cells, reducing stomach acid and impairing vitamin B12 absorption, according to Nature Reviews Disease Primers

Gomes 2014)

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Indeed, insulin-stimulated phosphorylation of multiple TBC1D4 phosphosites was impaired in insulin-resistant muscle from diabetic or TNF-infused patients [99,100], and conversely, exercise-induced phosphorylation of TBC1D4 S711 was required for improved insulin action in mice [101,102]