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Abstract Calcium oxalate (CaOx) is the most common type of kidney stone, and its crystal deposition can induce oxidative stress, inflammatory responses, and cell death

doi: 10.1186/s12906-018-2409-0 CrossRef Google Scholar View reference in article 12 AllaireA

In its reduced tripeptide form (GSH) composed of glutamine, glycine, and cysteine it is active, stable, and capable of interacting directly with the skins cellular systems

Future research should conduct stratified intervention trials based on vitamin-deficient populations to clarify the characteristics of the beneficiary groups, explore appropriate supplementation doses and treatment courses, seek a balance between effectiveness and safety, pay attention to the synergistic effects of combined vitamin use and their interactions with existing antifibrotic drugs, focus on in-depth exploration of mechanisms, explore the application of vitamins in regulating autophagy, mitochondrial function, epigenetic modifications and other aspects in liver protection, and combine emerging technologies to identify biomarkers that predict vitamin responsiveness, achieving targeted and precise intervention