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One survey found that over 62% of individuals supplementing with intranasal glutathione reported health benefits for either multiple chemical sensitivities, allergies, sinusitis, Parkinsons disease, Lyme disease or fatigue

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It has been reported that taVNS may inhibit peripheral inflammatory responses by modulating the 7nAChR/JAK2/STAT3 signaling pathway in the spleen, reducing the release of chemokine C-X-C Motif Chemokine Ligand 1 (CXCL1) and exerting anti-inflammatory effects, thereby improving LPS-induced depressive-like behaviors in rats (105)