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[17] In January 2023, the US FDA prescription label for Rybelsus was updated to reflect that it can be used as a first-line treatment for adults with type 2 diabetes

Here, we analyzed CNV lesion numbers and sizes in a large number of agematched (6weekold) mice and could show that targeting Nlrp3 or Il1r1 significantly reduced CNV lesion numbers (but not CNV lesion sizes), while targeting Il18 did not show a statistically significant change in either CNV lesion numbers or their size (Fig 8A and B, and Appendix Fig S5A and B)

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[DOI] [PubMed] [Google Scholar] 82.Tajik N., Frech M., Schulz O., Schlter F., Lucas S., Azizov V., Drholz K., Steffen F., Omata Y., Rings A., et al