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Taken together, the above results suggest that several convergent pathways participate in the modulation of lifespan in worms fed a HGD

When cysteine is limiting, we found that GCLC instead ligates glutamate to alternative amino acids to prevent the toxic accumulation of glutamate and ROS generation

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Cardiometabolic outcome trials Prospective study of older adults (mean age 68 years) using liraglutide 3 mg once daily for 24 weeks found improved body composition with reductions in central fat mass, and preserved muscular performance [86, 87], explained by increased myogenesis in myoblasts [88], and the recruitment of skeletal muscle microvasculature [89]