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CJC-1295 with DAC weekly dosing schedule Phase Initiation Window Weeks 1-2 Weekly dose 500-1,000 mcg once weekly Notes Start low to assess tolerance

Role of iNOS in osteoarthritis: Pathological and therapeutic aspects

The preclinical evidence is robust, consistent, and mechanistically plausible, but the gap between rat sciatic nerve transection models and human diabetic neuropathy is significant