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Clin Hemorheol Microcirc 40:235242 Ding J, Sullivan DA (2012) Aging and dry eye disease

PER 1, the main clock protein, has been reported to regulate the transcription levels of glucose transporter sodium-glucose cotransporter 1 (SGLT1) in proximal tubule cells [148], and the circadian clock located in podocytes could control the expression of the Rho GTPase activating protein 24 ( ARHGAP24 ) gene associated with predisposition to diabetic nephropathy in both T1DM and T2DM [146]