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Given the hydrolysis deficiency of CydDC E500Q and the associated conformational differences observed between turnover datasets of the wild-type and CydDC E500Q variants, we assign the consistently copurified nucleotide bound to NBS C as ATP

After 24 h of transfection, the cells were incubated with IPA and indole-3-methyl acetate (MelAA) at the indicated doses for an additional 6 h before analysis

However, the enzyme glutathione peroxidase within the human body can mitigate this damage, thereby protecting the macrophages

Trilling et al , 2011) and HCMV (LeTrilling et al , 2020) induce STAT2 degradation along the ubiquitinproteasome pathway (UPS)