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Short-term, they're useful

So even though glutathione has a short half-life in the bloodstream, doctors still recommend it because of its ability to quickly enter tissues, replenish glutathione stores inside the cells, and create measurable health benefits, just like this study showed

Reduced myostatin signaling in preclinical MOTS-c work

On the other hand, antioxidants can protect the cells from incident radiation through specialized pigments and control the levels of reactive species which otherwise might cause a cascade of reactions and lead to the generation of pathological oxidants [63]