glutathione glutamine meaning synthesis from glycine and glutamine; 'retro-control' by Glutamine reliance in cell metabolism

Clin Cancer Res 22(21):52875299 Lockman PR et al (2010) Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer

M.Beyk-KhormiziA.AmiriM

The RAW 264.7 cells were treated with FONE (0, 16.7, and 20 g/mL), with catalase (0, 5, and 15 U/mL) or 3-AT (0, 5, and 15 U/mL) for 24 h and then subjected for the Cyto-ID autophagy detection

For instance, LePHGPX in transgenic tobacco plants protected against DNA fragmentation, membrane integrity loss, and oxidative stress induced by necrotrophic fungi, mirroring anti-apoptotic roles observed in animals (Chen et al., 2004)