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SKU: 65590207644
Price: 29.50 USD
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Description

A negative feedback regulation of MTORC1 activity by the lysosomal Ca 2+ channel MCOLN1 (mucolipin 1) using a CALM (calmodulin)-dependent mechanism

Oridinon (Ori), a natural terpenoid derived from the plant Isodon rubescens (Hemsl.), can increase cardiac Gln levels and inhibit the decline of ATP/ADP ratio, protecting cardiomyocytes and reducing infarct size in a rat model of myocardial injury