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Description

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Step 4: Pinch a fold of skin at the injection site with your non-dominant hand

It is widely studied in preclinical models for its role in extracellular matrix remodeling , fibroblast activation , and gene expression regulation

In untreated slices, GFAP expression was reduced at 1 week (49.5% 10.02%, p = 0.0089), 3 weeks (62.66% 7.61%, p = 0.049) and 5 weeks (20.43% 3.49%, p = 0.00008) compared to GFAP expression at 24 h (100% 17.6%)