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For MorphoQuant analysis, picrosirius red (PSR)-stained slides were prepared and scanned at X20 magnification

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In 12 newly diagnosed LN patients, synbiotic administration induced significant alterations in gut microbiota composition: the relative abundance of pathogenic bacteria (including Prevotella, Bacteroides , and unclassified Enterobacteriaceae ) decreased, whereas beneficial bacterial populations (such as Actinobacteria and Firmicutes ) showed marked increases [95]

These results indicate that TLYYH effectively counteracts DSS-induced dysbiosis by restoring the balance between dominant bacterial phyla and promoting microbial homeostasis