glutathione reductase extract The Selenoprotein Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities Assay for quantitative determination of

Miotto G, Rossetto M, Di Paolo ML, Orian L, Venerando R, Roveri A, et al

The catalytic antioxidative efficiency of ZMTP nanosheets was further compared with natural enzymes (Mn-SOD and catalase) and typical nanocatalyst (CeO 2 nanoparticles), as well as several conventional molecular antioxidants (ascorbic acid, gallic acid, and reduced form of glutathione)

Moreover, in lipopolysaccharide (LPS)-treated mice or primary microglial cultures, increasing NADH levels reversed the protective effects of glycolytic inhibition, driving NF-B-mediated proinflammatory gene expression (IL1, IL6, and iNOS) through dimerization of the NAD(H)-sensitive transcriptional corepressor CtBP [66]

However, in pathological conditions, excess NO can react with superoxide to form ONOO , a potent oxidant that can nitrate tyrosine residues in proteins and damage lipids and DNA [52]