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But it is not a problem that just older men struggle with or have concerns or anxieties about: a 2013 survey of men seeking medical care at a urology center in Italy found that one of four men were under the age of 40,[2] while a 2017 publication from a sexual health and endocrinology center at the University of Florence reported that the percentage of men under 40 seeking care for ED had tripled from 2011 to 2014, increasing to 15%.[3] With the stress of the global pandemic, loss of jobs, social isolation, and related lifestyle coping behaviors, it is likely that beyond 2020 these statistics will continue to be increasingly bleak

All current evidence is from animal or in vitro models

These approaches could regenerate functional spermatogenic tissue in individuals with severe EED-induced reproductive damage

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