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Keywords: Alzheimers disease, amyloid -protein, extrasynaptic N-Methyl-D-aspartate receptor, memantine, tau protein INTRODUCTION Alzheimers disease (AD) is a neurodegenerative pathology of severe prognosis, currently incurable, and highly prevalent in aged people [1]

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Its ability to promote neuronal survival and their cognitive function in animal models offers hope for halting or even reversing the progression of this debilitating condition