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This is illustrated by a potentially influential report describing changes in proteinprotein interactions induced by the formation of spatial memory (Nelson et al., This study demonstrates the value of combining traditional biochemical and modern proteomic approaches with behavioral testing to provide information regarding neuronal proteinprotein interactions that participate in spatial memory formation that could not have been obtained without prior knowledge of at least one binding partner in these interactions

doi: 10.1038/srep29716 30 ZhangY.LiuX.HanL.GaoX.LiuE.WangT

Hexokinases (HKs), essential enzymes in glucose metabolism, catalyze the phosphorylation of imported glucose to yield glucose-6-phosphate (G-6-P) 32,33

Dreesen O, Wang AS (2018) Biomarkers of cellular senescence and skin aging