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Additionally, external and iatrogenic factors such as radiation and xenobiotics are increasingly recognized as disruptors of gutbrain homeostasis, contributing to neurotoxicity and immune dysregulation

We also highlight the in vivo importance of Set7/9 in ROS-related diseases

Mulder, D

Although the propargylamine moiety might be responsible for the protection afforded by clorgyline and l -deprenyl, the lack of any protective effect of pargyline in our system and in some other neuronal models (see Mytilineou et al, 1997) would indicate it not to be a general property of all propargylamine derivatives