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For this, both utilization of substrate (MG) and generation of product (D-lactate) were measured in the same reaction mixture and a reverse correlation has been observed between them (Fig

Adjusting pH to a neutral range, where possible, can slow this decline, especially for sensitive products

Such minor stress, which, for example, can be induced by pharmaceutical agents, can boost mitochondrial turnover and activate defensive mechanisms (Haigis and Yankner, 2010)